Our lab focuses on uncovering and harnessing the vast genetic diversity of RNA-guided systems – from fundamental discovery to real-world applications. We start by identifying novel systems from nature’s genetic treasure troves, then dissect their mechanisms at the molecular and structural level. Building on this knowledge, we drive tool development and protein engineering to create powerful, versatile molecular tools. Ultimately, we aim to translate these innovations into therapeutic applications, developing next-generation strategies to treat diseases in both animal models and humans.

​

​

 

 

 

 

 

 

​

​

​

​

​

Our research is like exploring an iceberg—while we’ve uncovered the tip, there’s still a vast, hidden world beneath the surface waiting to be understood. Building on what we already know, such as CRISPR-Cas systems and AI-driven structure prediction, We are diving into the unknown.

 

This includes uncovering the secrets of "biological dark matter," understanding the ancient RNA world, and mapping the intricate ways molecules interact. By harnessing AI and the latest technologies, my work connects key areas like genetic diversity, bacterial immunity, and the molecular basis of emotions to solve urgent challenges such as controlling pandemics and developing new therapies. Our ultimate goal is to drive biology into a new era, transforming how we understand life and opening doors to revolutionary breakthroughs.

​

​

​

​

​

​